Research summary
Research Hub5-Amino-1MQ
Preclinical — 4 studies
5-Amino-1MQ is a small-molecule NNMT inhibitor studied for its role in metabolic efficiency and energy expenditure research.
Being studied for
- NNMT inhibition
- Metabolic efficiency pathways
Published Research
Evidence profile
Predominantly preclinical
4 cited publications
Findings below belong to the studies that reported them. They describe the material and conditions those authors used, not this product, and not an outcome to expect.
Additional indexed literature (4)
- Preclinical · Mechanistic studyNicotinamide n-methyltransferase inhibitor synergizes with sodium-glucose cotransporter 2 inhibitor to protect renal tubular epithelium in experimental models of type 2 diabetes mellitus
Yang Y et al. · Journal of diabetes and its complications · 2025 · PMID 39848127
- Preclinical · Mechanistic studyReduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
Dimet-Wiley A et al. · Scientific reports · 2022 · PMID 35013352
- Preclinical · Mechanistic studyCombined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice
Sampson CM et al. · Scientific reports · 2021 · PMID 33707534
- Preclinical · Mechanistic studySmall molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle
Neelakantan H et al. · Biochemical pharmacology · 2019 · PMID 30753815
Published studies summarised here concern the specific investigational or pharmaceutical materials and study conditions described by their authors. Their findings are not performance claims for Cobalt Peptides material. Citations verified against PubMed on 2026-08-09.
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