Research summary
Research HubPinealon
Clinical — 10 studies
Pinealon is a synthetic tripeptide studied in aging and neuroprotection research for its effects on neuronal signaling pathways.
Being studied for
- Neuronal aging research
- Cognitive decline models
- Cellular stress resistance
Published Research
Evidence profile
Controlled human evidence
10 cited publications · 1 primary trial
Findings below belong to the studies that reported them. They describe the material and conditions those authors used, not this product, and not an outcome to expect.
Supporting evidence
[The peptide correction of neurotic disorders among professional truck-drivers]
Bashkireva AS et al. · Advances in gerontology = Uspekhi gerontologii · 2012
The study reportedThe best effect was obtained in case of combined application of several cytogens (pinealon and vezugen), which were optimally selected regarding the effect of each adverse occupational factor on a target organ or system.
Additional indexed literature (9)
- Preclinical · Mechanistic studyNeuroprotective Effects of Tripeptides-Epigenetic Regulators in Mouse Model of Alzheimer's Disease
Khavinson V et al. · Pharmaceuticals (Basel, Switzerland) · 2021 · PMID 34071923
- Preclinical · Mechanistic study[Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon]
Mendzheritskiĭ AM et al. · Advances in gerontology = Uspekhi gerontologii · 2014 · PMID 25051764
- Preclinical · Mechanistic studyPinealon protects the rat offspring from prenatal hyperhomocysteinemia
Arutjunyan A et al. · International journal of clinical and experimental medicine · 2012 · PMID 22567179
- Preclinical · Mechanistic study[Analysis of some parameters of biological age and adaptation possibilities of workers of locomotive brigades]
Nazimko VA et al. · Advances in gerontology = Uspekhi gerontologii · 2012 · PMID 22708445
- Preclinical · Mechanistic study[Effects of introduction of short peptides before carotid artery occlusion on behaviour and caspase-3 activity in the brain of old rats]
Mendzheritskiĭ AM et al. · Advances in gerontology = Uspekhi gerontologii · 2011 · PMID 21809624
- Preclinical · Mechanistic studyPinealon increases cell viability by suppression of free radical levels and activating proliferative processes
Khavinson V et al. · Rejuvenation research · 2011 · PMID 21978084
- Preclinical · Mechanistic studyPenetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA
Fedoreyeva LI et al. · Biochemistry. Biokhimiia · 2011 · PMID 22117547
- Preclinical · Mechanistic study[Biological activity of regulatory peptides in model experiments in vitro]
Kozina LS et al. · Advances in gerontology = Uspekhi gerontologii · 2008 · PMID 18546826
- Preclinical · Mechanistic study[Investigation of antihypoxic properties of short peptides]
Kozina LS · Advances in gerontology = Uspekhi gerontologii · 2008 · PMID 18546825
Published studies summarised here concern the specific investigational or pharmaceutical materials and study conditions described by their authors. Their findings are not performance claims for Cobalt Peptides material. Citations verified against PubMed on 2026-08-09.
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