Research summary
Research HubMOTS-c
Clinical — 10 studies
MOTS-c is a mitochondrial-derived peptide investigated for its role in metabolic regulation and cellular stress responses.
Being studied for
- Cellular stress adaptation
- Metabolic signaling pathways
- Mitochondrial communication research
Published Research
Evidence profile
Preclinical, with limited uncontrolled human reports
10 cited publications
Findings below belong to the studies that reported them. They describe the material and conditions those authors used, not this product, and not an outcome to expect.
Additional indexed literature (10)
- Clinical · Mechanistic studySerum MOTS-c levels remain unchanged in patients with preeclampsia
Tok A et al. · Ginekologia polska · 2023 · PMID 39469962
- Preclinical · Mechanistic studyMOTS-c attenuates airway barrier dysfunction in allergic asthma by inhibiting epithelial apoptosis via Nrf2 pathway
Zhang W et al. · International immunopharmacology · 2025 · PMID 40472776
- Preclinical · Mechanistic studyMOTS-C levels ın ındividuals with and without obesity and ıts association with ınflammation, insulin resistance and endothelial dysfunction
Ozkaya DY et al. · Archives of endocrinology and metabolism · 2025 · PMID 41004666
- Preclinical · Mechanistic studyMOTS-c-modified functional self-assembly peptide hydrogels enhance the activity of nucleus pulposus-derived mesenchymal stem cells of intervertebral disc degeneration
Lin Y et al. · Materials today. Bio · 2025 · PMID 40510834
- Preclinical · Mechanistic studyMOTS-c attenuates lung ischemia-reperfusion injury via MYH9-Dependent nuclear translocation and transcriptional activation of antioxidant genes
Li X et al. · Redox biology · 2025 · PMID 40403491
- Preclinical · Mechanistic studyMOTS-c attenuates mitochondrial dysfunction induces pyroptosis and cartilage degradation in osteoarthritis via an Nrf2-Dependent Mechanism
Li K et al. · Free radical biology & medicine · 2025 · PMID 41043625
- Preclinical · Mechanistic studyMOTS-c Promotes Glycolysis via AMPK-HIF-1α-PFKFB3 Pathway to Ameliorate Cardiopulmonary Bypass-induced Lung Injury
Shen Z et al. · American journal of respiratory cell and molecular biology · 2025 · PMID 40035775
- Preclinical · Mechanistic studyMOTS-c mimics exercise to combat diabetic liver fibrosis by targeting Keap1-Nrf2-Smad2/3
Chen F et al. · Scientific reports · 2025 · PMID 40425777
- Preclinical · Mechanistic studyNovel function of MOTS-c in mitochondrial remodelling contributes to its antiviral role during HBV infection
Lin C et al. · Gut · 2024 · PMID 37788894
- Preclinical · Mechanistic studyMOTS-c and aerobic exercise induce cardiac physiological adaptation via NRG1/ErbB4/CEBPβ modification in rats
Yuan J et al. · Life sciences · 2023 · PMID 36584915
Published studies summarised here concern the specific investigational or pharmaceutical materials and study conditions described by their authors. Their findings are not performance claims for Cobalt Peptides material. Citations verified against PubMed on 2026-08-09.
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