Research summary
Research HubKPV
Preclinical — 10 studies
KPV is a tripeptide fragment derived from alpha-melanocyte-stimulating hormone (α-MSH) that has been investigated for its anti-inflammatory and immunomodulatory properties in preclinical research.
Being studied for
- Inflammation modulation
- Gut and intestinal barrier research
- Immune response regulation
- Cytokine signaling pathways
Published Research
Evidence profile
Predominantly preclinical
10 cited publications
Findings below belong to the studies that reported them. They describe the material and conditions those authors used, not this product, and not an outcome to expect.
Additional indexed literature (10)
- Preclinical · Mechanistic studyLysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells
Lee JY et al. · Cytotechnology · 2026 · PMID 42064835
- Preclinical · Mechanistic studyNLRP3 autophagic degradation disruption in melanocytes contributes to vitiligo development
Zeng K et al. · Cell death and differentiation · 2026 · PMID 40935835
- Preclinical · Mechanistic studyInflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers
Cheng J et al. · Science advances · 2026 · PMID 41533788
- Preclinical · Mechanistic studyLysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway
Sung J et al. · Tissue & cell · 2025 · PMID 40073467
- Preclinical · Mechanistic studyPepT1-targeted nanodrug based on co-assembly of anti-inflammatory peptide and immunosuppressant for combined treatment of acute and chronic DSS-induced ColitiS
Zhang D et al. · Frontiers in pharmacology · 2024 · PMID 39211778
- Preclinical · Mechanistic studyKPV and RAPA Self-Assembled into Carrier-Free Nanodrugs for Vascular Calcification Therapy
Zhang L et al. · Advanced healthcare materials · 2024 · PMID 39252648
- Preclinical · Mechanistic studyA KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon
Zhao Y et al. · Acta biomaterialia · 2022 · PMID 35245681
- Preclinical · Mechanistic studySkin-adaptive film dressing with smart-release of growth factors accelerated diabetic wound healing
Zhao Y et al. · International journal of biological macromolecules · 2022 · PMID 36240893
- Preclinical · Mechanistic studyIn situ mucoadhesive hydrogel capturing tripeptide KPV: the anti-inflammatory, antibacterial and repairing effect on chemotherapy-induced oral mucositis
Shao W et al. · Biomaterials science · 2021 · PMID 34846053
- Preclinical · Mechanistic studySelf-Cross-Linked Hydrogel of Cysteamine-Grafted γ-Polyglutamic Acid Stabilized Tripeptide KPV for Alleviating TNBS-Induced Ulcerative Colitis in Rats
Sun J et al. · ACS biomaterials science & engineering · 2021 · PMID 34547895
Published studies summarised here concern the specific investigational or pharmaceutical materials and study conditions described by their authors. Their findings are not performance claims for Cobalt Peptides material. Citations verified against PubMed on 2026-08-09.
KPV is an experimental research peptide studied in laboratory settings. It is not approved as a medicinal product for human use.
Notice
All information on this page is provided strictly for laboratory research and educational purposes only.