Research summary
Research HubDSIP (Delta Sleep-Inducing Peptide)
Clinical — 10 studies
DSIP is a neuropeptide studied for its role in sleep regulation, stress response, and neuroendocrine signaling.
Being studied for
- Sleep architecture research
- Neuroendocrine stress pathways
- Cognitive recovery mechanisms
Published Research
Evidence profile
Controlled human evidence
10 cited publications · 2 primary trials
Findings below belong to the studies that reported them. They describe the material and conditions those authors used, not this product, and not an outcome to expect.
Supporting evidence
Acute and delayed effects of DSIP (delta sleep-inducing peptide) on human sleep behavior
Schneider-Helmert D et al. · International journal of clinical pharmacology, therapy, and toxicology · 1981
The study reportedThe results suggest that DSIP in humans is also efficacious by sustaining natural sleep functions. The compound was well-tolerated and no psychologic, physiologic, or biochemical side effects were observed.
The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep
Schneider-Helmert D et al. · Experientia · 1981
The study reportedSleep-promoting effects occurred only in the second hour after injection, in the first hour a slight arousing effect was indicated. The study corroborates the findings of previous investigations in healthy subjects and shows that DSIP has a normalizing influence on human sleep regulation.
Additional indexed literature (8)
- Clinical · Mechanistic studyComparison of DSIP- (delta sleep-inducing peptide) and P-DSIP-like (phosphorylated) immunoreactivity in cerebrospinal fluid of patients with senile dementia of Alzheimer type, multi-infarct syndrome, communicating hydrocephalus and Parkinson's disease
Ernst A et al. · Journal of neurology · 1987 · PMID 2448424
- Preclinical · Mechanistic studyDelta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke
Tukhovskaya EA et al. · Molecules (Basel, Switzerland) · 2021 · PMID 34500605
- Preclinical · Mechanistic studyDelta-sleep inducing peptide entrapment in the charged macroporous matrices
Sukhanova TV et al. · Materials science & engineering. C, Materials for biological applications · 2014 · PMID 25063142
- Preclinical · Mechanistic studyAntiepileptic activity of delta sleep-inducing peptide and its analogue in metaphit-provoked seizures in rats
Stanojlović OP et al. · Seizure · 2005 · PMID 15911358
- Preclinical · Mechanistic studyDelta sleep inducing peptide (DSIP): effect on respiration activity in rat brain mitochondria and stress protective potency under experimental hypoxia
Khvatova EM et al. · Peptides · 2003 · PMID 12668217
- Preclinical · Mechanistic studyStructure-activity relationship in the effects of delta-sleep-inducing peptide (DSIP) on rat sleep
Obál F Jr et al. · Pharmacology, biochemistry, and behavior · 1986 · PMID 3754970
- Preclinical · Mechanistic studySome pharmacological effects of delta-sleep-inducing peptide (DSIP)
Scherschlicht R et al. · European neurology · 1984 · PMID 6548967
- Preclinical · Mechanistic studyCharacterization, properties and multivariate functions of delta-sleep-inducing peptide (DSIP)
Schoenenberger GA · European neurology · 1984 · PMID 6548966
Published studies summarised here concern the specific investigational or pharmaceutical materials and study conditions described by their authors. Their findings are not performance claims for Cobalt Peptides material. Citations verified against PubMed on 2026-08-09.
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