Scientific Reference
HCG (Human Chorionic Gonadotropin)
Evidence profile: Controlled human evidence
Human Chorionic Gonadotropin (HCG) is a heterodimeric glycoprotein hormone produced by the placenta during pregnancy. It comprises an alpha subunit shared with LH, FSH and TSH, and a distinct beta subunit that gives it its biological specificity. It acts as a luteinising hormone analogue, binding LH receptors and activating steroidogenesis, and is studied in endocrinology on that basis. Licensed medicines containing chorionic gonadotropin exist and are prescribed by clinicians; the material supplied here is a research compound and is not one of them.
Published Research
Clomiphene citrate and human chorionic gonadotropin are both effective in restoring testosterone in hypogonadism: a short-course randomized study
Habous M et al. · BJU international · 2018 · Clinical
PMID 29772111 — View on PubMedLate-onset hypogonadism: the advantages of treatment with human chorionic gonadotropin rather than testosterone
La Vignera S et al. · The aging male : the official journal of the International Society for the Study of the Aging Male · 2016 · Clinical
PMID 26488941 — View on PubMedGonadotropins for pubertal induction in males with hypogonadotropic hypogonadism: systematic review and meta-analysis
Alexander EC et al. · European journal of endocrinology · 2024 · Review
PMID 38128110 — View on PubMedA combined analysis of data to identify predictive factors for spermatogenesis in men with hypogonadotropic hypogonadism treated with recombinant human follicle-stimulating hormone and human chorionic gonadotropin
Warne DW et al. · Fertility and sterility · 2009 · Review
PMID 18930225 — View on PubMed