Research Comparison
Pinealon (EDR) vs SS-31 (Elamipretide)
A side-by-side research comparison of Pinealon (EDR) and SS-31 (Elamipretide) drawn from Cobalt Peptides' peptide database records.
Pinealon (EDR)
Pinealon (Glu-Asp-Arg/EDR) is a synthetic tripeptide bioregulator developed in Russia that demonstrates unique DNA-interaction capabilities for neuroprotection and cognitive enhancement. Research suggests benefits for traumatic brain injury recovery, age-related cognitive decline, and cellular aging processes through direct gene expression modulation. Studies have shown that Pinealon exerts neuroprotective effects through MAPK/ERK pathway modulation, reduced neuroinflammation, and enhanced NMDA receptor expression in hippocampal regions. Its ability to directly interact with DNA and influence gene expression makes it distinct from other peptide bioregulators.
SS-31 (Elamipretide)
SS-31 (elamipretide) is a small aromatic-cationic tetrapeptide that localises to the inner mitochondrial membrane. Rather than scavenging reactive oxygen species diffusely as conventional antioxidants do, it binds cardiolipin — a phospholipid required for the structural integrity of the electron transport chain — and the published literature describes this targeted interaction in the context of mitochondrial function. SS-31 is not an approved medicine in the United Kingdom. Supplied strictly as a research compound for laboratory use.