Research Comparison
AOD-9604 vs SLU-PP-332
A side-by-side research comparison of AOD-9604 and SLU-PP-332 drawn from Cobalt Peptides' peptide database records.
AOD-9604
AOD-9604 is a modified 17-amino acid fragment derived from the C-terminal region of human growth hormone (hGH 176–191), with the addition of an N-terminal tyrosine residue. It was specifically engineered to isolate the lipolytic and anti-lipogenic properties of growth hormone while avoiding its anabolic and endocrine effects. Unlike full-length hGH, AOD-9604 does not bind to the growth hormone receptor, does not elevate IGF-1 levels, and does not impair glucose metabolism. This selective mechanism has made it a focus of research in obesity, fat metabolism, and cartilage repair, offering a more targeted metabolic profile without the systemic hormonal effects associated with growth hormone.
SLU-PP-332
SLU-PP-332 is a synthetic small-molecule compound that functions as a pan-estrogen-related receptor (ERR) agonist with preferential activity at ERRα. Often described as an 'exercise mimetic,' it activates metabolic gene expression programmes typically engaged during aerobic exercise without requiring physical activity. By enhancing mitochondrial biogenesis, fatty acid oxidation, and energy expenditure, SLU-PP-332 has demonstrated significant preclinical effects including weight reduction, improved endurance, and reversal of age-related mitochondrial dysfunction. It remains a research-only compound with no human clinical trial data currently available.