Research Comparison
AOD-9604 vs LC120
A side-by-side research comparison of AOD-9604 and LC120 drawn from Cobalt Peptides' peptide database records.
AOD-9604
AOD-9604 is a modified 17-amino acid fragment derived from the C-terminal region of human growth hormone (hGH 176–191), with the addition of an N-terminal tyrosine residue. It was specifically engineered to isolate the lipolytic and anti-lipogenic properties of growth hormone while avoiding its anabolic and endocrine effects. Unlike full-length hGH, AOD-9604 does not bind to the growth hormone receptor, does not elevate IGF-1 levels, and does not impair glucose metabolism. This selective mechanism has made it a focus of research in obesity, fat metabolism, and cartilage repair, offering a more targeted metabolic profile without the systemic hormonal effects associated with growth hormone.
LC120
LC120 is a small molecule compound identified as a pan-estrogen-related receptor (ERR) agonist, targeting ERRα, ERRβ, and ERRγ. It is used in metabolic research to investigate mitochondrial function, energy expenditure, and oxidative metabolism. By activating ERR pathways, LC120 enhances transcriptional programmes associated with mitochondrial biogenesis and fatty acid oxidation. It is particularly relevant in studies focused on endurance, metabolic flexibility, and cellular energy efficiency.