Research Comparison
AHK-Cu (Copper Tripeptide-3) vs Epitalon (Epithalon, AEDG)
A side-by-side research comparison of AHK-Cu (Copper Tripeptide-3) and Epitalon (Epithalon, AEDG) drawn from Cobalt Peptides' peptide database records.
AHK-Cu (Copper Tripeptide-3)
AHK-Cu (Copper Tripeptide-3) is a synthetic copper-binding tripeptide composed of alanine, histidine, and lysine complexed with a divalent copper ion (Cu²⁺). It is structurally analogous to GHK-Cu, differing by a single amino acid substitution at the N-terminus, which contributes to its more targeted activity in dermal papilla cells and hair follicles. The compound is primarily investigated for its role in hair growth and skin regeneration. It has demonstrated the ability to stimulate follicular activity, enhance vascular signaling, and modulate pathways associated with hair miniaturization. In addition to hair-focused applications, AHK-Cu supports fibroblast activation and collagen synthesis, contributing to improved skin structure and repair.
Epitalon (Epithalon, AEDG)
Epitalon (Epithalon, AEDG) is a synthetic tetrapeptide derived from a naturally occurring pineal gland peptide, composed of four amino acids (Ala-Glu-Asp-Gly). It has been extensively studied in Russian research for its role in regulating aging processes, particularly through telomerase activation and circadian rhythm modulation. The peptide is associated with cellular longevity, improved sleep regulation via melatonin production, and systemic anti-aging effects. Research suggests it may influence gene expression, antioxidant systems, and cellular repair pathways, with effects observed even at extremely low (microgram-level) concentrations.